Events

Tip Speed or P/V Don’t Cut it Anymore - Scaling-up Bioprocesses the Right Way

Scaling up bioprocesses is a challenging process that requires a careful balance between equipment design and operational capabilities. Key factors influencing shear, mixing, and oxygen transfer must be considered. Traditional parameters like tip speed or power per volume (P/V) are no longer adequate. As bioprocessing grows more complex and regulatory demands tighten, it’s crucial to consider othe...

Accelerating Crystallization Process Scale-Up with Mixing Intelligence

Crystallization plays a critical role in pharmaceutical and chemical manufacturing, directly impacting product purity, particle size distribution (PSD), and downstream process efficiency. However, the path from lab-scale success to full-scale production is fraught with challenges—especially when mixing dynamics, yield, and crystallization kinetics vary across equipment scales.

Building ROMs and Digital Twins using Python Libraries

Digital twins are virtual representations of physical objects, leveraging computational models like CFD and FEA. While these full-scale models are powerful, they come with significant challenges—they are costly, require expert users, and consume extensive computational resources. Reduced Order Models (ROMs) simplify these complexities by creating cost-effective, user-friendly models that maintain ...